Environmental factors can play an important role in the development of autoimmune thyroiditis (AT) and other autoimmune diseases. This article reviews the role of heavy metals and infectious agents in AT. Memory T lymphocytes can be used as biomarkers of susceptibility to mercury and other inflammation triggers in individual patients. If metal allergy is found, the patient should avoid all exposure to the allergenic substance. Mercury-allergic patients may benefit from replacement of dental amalgam.
Mercury levels in plasma and urine after removal of all amalgam restorations: the effect of using rubber dams
This study showed that dental amalgam had a statistically significant impact on the mercury levels found in plasma and urine in the patients tested, and that the use of a rubber dam during removal of all amalgam restorations significantly reduced the peak of mercury in plasma following removal.